Eliquis: 7 Foods to avoid while on Eliquis (in Detail)

Medically reviewed by Dr. Ramesh Gaddam, M.D. — Written by Sumalatha, D.N.H.E

Eliquis is a medicine that helps prevent blood clots. It’s important to watch what you eat while taking it because some foods can affect how well it works. Knowing which foods to avoid can help keep you safe and make sure the medicine does its job correctly.

1. Foods High in Vitamin K

 

foods to avoid while on Eliquis - brussels-sprouts-sprouts-cabbage
Vitamin K Rich Foods

 

Vitamin K is essential for blood clotting, which is exactly what Eliquis helps to control.

Eliquis works by preventing blood clots, so consuming too much Vitamin K can counteract the effects of the medication.

This means that eating foods high in Vitamin K can make Eliquis less effective, putting you at risk for blood clots.

Role of Vitamin K in Blood Clotting

Vitamin K is crucial for the body’s process of forming blood clots.

It helps produce proteins that enable blood to clot and stop bleeding.

While this is normally beneficial, when taking a blood thinner like Eliquis, too much Vitamin K can reduce the medication’s ability to prevent dangerous clots.

Impact on Eliquis Efficacy

When you consume foods high in Vitamin K, it can interfere with Eliquis by promoting clot formation, which Eliquis is trying to prevent.

This interaction can diminish the medication’s effectiveness and increase the risk of blood clots, which can lead to serious health issues such as strokes or heart attacks.

Examples of High Vitamin K Foods to Limit

It’s important to be mindful of your intake of Vitamin K-rich foods. While you don’t need to completely avoid them, moderation is key.

Leafy Greens:

Foods like spinach, kale, and Swiss chard are very high in Vitamin K. A single serving of these vegetables can contain more than the daily recommended amount of Vitamin K. It’s best to limit these to small portions and not consume them in large quantities regularly.

Broccoli and Brussels Sprouts:

These vegetables are also rich in Vitamin K. Including them occasionally in your diet is fine, but eating them in large amounts frequently can interfere with Eliquis.

Other Cruciferous Vegetables:

Vegetables such as cabbage, cauliflower, and bok choy also contain Vitamin K. They should be consumed in moderation to avoid counteracting the effects of Eliquis.

 

By being aware of the Vitamin K content in these foods and consuming them in moderation, you can help ensure that Eliquis works effectively to prevent blood clots. Always consult with your healthcare provider for personalized dietary advice while on this medication.

2. Alcohol

 

foods to avoid while on eliquis - alcohol
Alcohol

 

Alcohol can have a significant impact on the effectiveness and safety of Eliquis.

While moderate alcohol consumption may be acceptable for some individuals, it is important to understand the potential risks and how alcohol interacts with this medication.

Interaction Between Alcohol and Eliquis

Drinking alcohol while taking Eliquis can increase the risk of bleeding.

Both alcohol and Eliquis affect blood clotting, and when combined, their effects can be amplified. This means that even minor cuts or injuries can lead to excessive bleeding, which can be dangerous.

Increased Risk of Bleeding

One of the main concerns with consuming alcohol while on Eliquis is the heightened risk of bleeding.

Alcohol can irritate the stomach lining, which, combined with the blood-thinning properties of Eliquis, can lead to gastrointestinal bleeding.

Additionally, alcohol can impair judgment and coordination, increasing the likelihood of falls or injuries that could result in bleeding.

Recommendations for Alcohol Consumption

It’s important to discuss alcohol use with your healthcare provider while taking Eliquis. They can provide personalized advice based on your overall health and medical history. Generally, moderation is key.

Moderation Guidelines:

For many people, moderate drinking means up to one drink per day for women and up to two drinks per day for men. However, even this level of consumption should be discussed with your doctor.

Types of Alcohol to Avoid:

Certain types of alcohol may pose more risks. For example, drinks with high alcohol content or those that can irritate the stomach, such as hard liquor and strong cocktails, should be avoided or consumed very sparingly.

By understanding the interaction between alcohol and Eliquis, and following your healthcare provider’s recommendations, you can help minimize the risk of adverse effects and ensure that your medication works effectively.

3. Cranberry Products

 

foods to avoid while on eliquis - cranberry products
Cranberries

 

Cranberry products can interact with Eliquis, potentially increasing the risk of bleeding.

While cranberries are healthy in many ways, their interaction with blood-thinning medications like Eliquis requires careful attention.

Potential Interaction with Anticoagulants

Cranberries, especially in large amounts, can interact with anticoagulants.

The exact mechanism isn’t fully understood, but it’s believed that cranberries can affect the metabolism of these medications, potentially leading to an increased risk of bleeding.

Mechanism of Increased Bleeding Risk

Cranberries contain compounds that can inhibit certain enzymes involved in drug metabolism.

When these enzymes are inhibited, the levels of Eliquis in the bloodstream can rise, making the blood too thin and increasing the risk of bleeding.

This interaction can be particularly concerning for people taking Eliquis, as the medication is already designed to prevent clotting.

Forms of Cranberry to Be Cautious With

Cranberries come in various forms, and each can pose different risks when consumed in large amounts while taking Eliquis.

Cranberry Juice:

Drinking large quantities of cranberry juice can increase the risk of interaction. Even moderate consumption should be discussed with your healthcare provider.

Cranberry Supplements:

These often contain concentrated cranberry extract, which can have a stronger effect than cranberry juice or fresh cranberries. It’s best to avoid these supplements unless specifically advised by your doctor.

Fresh Cranberries and Dried Cranberries:

While these are generally safer in small amounts, it’s still important to consume them in moderation and discuss their use with your healthcare provider.

By being cautious with cranberry products and consulting with your healthcare provider, you can help manage the risk of bleeding and ensure that Eliquis works effectively. Always inform your healthcare provider about any cranberry products you consume regularly.

4. Grapefruit and Grapefruit Juice

 

foods to avoid while on eliquis - grapefruits
Grapefruits

 

Grapefruit and grapefruit juice can significantly affect how Eliquis works in your body.

These citrus fruits can interfere with the enzymes that metabolize Eliquis, potentially leading to dangerous side effects.

Impact on Drug Metabolism

Grapefruit contains compounds called furanocoumarins that inhibit cytochrome P450 3A4 (CYP3A4) enzymes in the liver and intestines.

These enzymes are crucial for breaking down many medications, including Eliquis.

When grapefruit inhibits these enzymes, it can cause higher levels of the medication to remain in the bloodstream.

Specific Enzymes Affected

The CYP3A4 enzymes are responsible for metabolizing many drugs.

By inhibiting these enzymes, grapefruit can slow the breakdown of Eliquis, leading to increased drug levels in the body.

This can enhance the effects of Eliquis, increasing the risk of bleeding and other side effects.

Resulting Changes in Eliquis Levels and Risk of Side Effects

When the metabolism of Eliquis is slowed, the drug stays in the body longer and at higher concentrations than intended.

This can lead to an increased risk of bleeding complications, such as gastrointestinal bleeding, nosebleeds, and in severe cases, internal bleeding.

It can also amplify other side effects like dizziness and weakness.

Recommendations for Grapefruit Consumption

To avoid these risks, it’s generally recommended to avoid grapefruit and grapefruit juice while taking Eliquis.

Complete Avoidance:

The safest approach is to avoid grapefruit and grapefruit juice entirely. This includes not only fresh grapefruit but also any products that contain grapefruit or its juice.

Checking Labels:

Be vigilant about reading food and drink labels to ensure they don’t contain grapefruit, especially in mixed fruit juices and flavored beverages.

By steering clear of grapefruit and grapefruit juice, you can help maintain safe and effective levels of Eliquis in your system. Always consult with your healthcare provider for specific advice regarding your diet and medication interactions.

5. Foods High in Omega-3 Fatty Acids

 

foods to avoid while on eliquis - omega-3 foods
Omega -3 Foods

 

Omega-3 fatty acids are known for their heart health benefits, but when you’re on Eliquis, it’s important to be aware of their blood-thinning properties.

Consuming large amounts of Omega-3s can enhance the effects of Eliquis, increasing the risk of bleeding.

Blood-Thinning Properties of Omega-3s

Omega-3 fatty acids, found in certain fish and plant sources, have natural blood-thinning effects.

They work by reducing the ability of blood platelets to clump together, which is beneficial for preventing clots but can be problematic when combined with Eliquis, a medication designed to prevent clots by thinning the blood.

Cumulative Effect with Eliquis

When you consume high levels of Omega-3s while taking Eliquis, the combined blood-thinning effects can make you more susceptible to bleeding.

This cumulative effect can increase the risk of bruising, nosebleeds, and more serious bleeding complications, such as gastrointestinal or internal bleeding.

Examples of Omega-3 Rich Foods to Moderate

While you don’t need to completely eliminate Omega-3 rich foods from your diet, it’s wise to consume them in moderation and discuss your intake with your healthcare provider.

Fatty Fish:

Fish like salmon, mackerel, sardines, and tuna are rich in Omega-3 fatty acids. It’s beneficial to limit your consumption to a few servings per week rather than daily.

Flaxseeds and Chia Seeds:

These seeds are excellent sources of plant-based Omega-3s. Using them sparingly in your diet is recommended, rather than in large quantities.

Fish Oil Supplements:

These supplements provide concentrated doses of Omega-3s and should generally be avoided unless prescribed by your healthcare provider, who can monitor your blood levels and adjust your Eliquis dosage if necessary.

 

By moderating your intake of Omega-3 rich foods and consulting with your healthcare provider, you can balance the benefits of these healthy fats with the need to maintain safe levels of blood thinning. Always inform your healthcare provider about any supplements you take, including fish oil.

6. Herbal Supplements and Teas

 

foods to avoid while on eliquis - Herbal Teas
Herbal Tea

Herbal supplements and teas can also interact with Eliquis, potentially increasing the risk of bleeding or affecting the medication’s efficacy.

Some herbs have natural blood-thinning properties or other effects that can interfere with Eliquis.

Common Herbal Supplements with Anticoagulant Effects

 

Certain herbal supplements are known to have blood-thinning properties, which can enhance the effects of Eliquis and increase bleeding risks. It’s crucial to be aware of these supplements and avoid them unless advised otherwise by your healthcare provider.

Ginkgo Biloba:

This herb is often used to improve cognitive function and circulation. However, it also has blood-thinning effects that can increase bleeding risk when taken with Eliquis.

 

Garlic:

While garlic is beneficial for heart health, it has natural anticoagulant properties. High doses of garlic supplements can exacerbate the blood-thinning effects of Eliquis.

 

St. John’s Wort:

Commonly used for depression and mood disorders, St. John’s Wort can affect the metabolism of various medications, including Eliquis, potentially reducing its effectiveness.

Herbal Teas with Potential Interactions

 

Herbal teas are popular for their health benefits, but some can interact with Eliquis. It’s important to consume these teas in moderation and consult your healthcare provider.

Green Tea:

Rich in Vitamin K, green tea can counteract the blood-thinning effects of Eliquis. Drinking large amounts can reduce the medication’s efficacy.

Chamomile:

Often used for its calming effects, chamomile can increase the risk of bleeding when consumed in large quantities due to its mild anticoagulant properties.

Recommendations for Use and Consultation with Healthcare Provider

 

To safely use herbal supplements and teas while taking Eliquis, follow these guidelines:

Consult Your Healthcare Provider:

Always inform your doctor about any herbal supplements or teas you are considering. They can provide personalized advice based on your health status and current medications.

Moderation:

If your healthcare provider approves the use of certain herbs or teas, consume them in moderation to minimize the risk of interactions.

Monitor for Side Effects:

Be vigilant for any signs of increased bleeding, such as easy bruising, prolonged bleeding from cuts, or unusual nosebleeds, and report these to your healthcare provider promptly.

By being cautious with herbal supplements and teas and seeking guidance from your healthcare provider, you can help ensure that Eliquis remains effective and safe in your treatment regimen.

7. Processed and Salty Foods

 

foods to avoid while on eliquis - Salty foods
Salty Foods

Processed and salty foods can negatively impact your overall cardiovascular health, which is particularly important to consider when taking Eliquis. These foods can affect blood pressure and fluid retention, potentially complicating your condition.

Influence on Blood Pressure and Fluid Retention

 

Processed and salty foods often contain high levels of sodium, which can lead to increased blood pressure and fluid retention. High blood pressure is a risk factor for various cardiovascular issues and can increase the risk of bleeding complications when on blood thinners like Eliquis.

Sodium’s Role:

 

  • Excess sodium causes the body to retain water, leading to increased blood volume and higher blood pressure.
  • This can put extra strain on blood vessels and the heart.

Impact on Heart Health:

 

  • High blood pressure and fluid retention can exacerbate existing heart conditions.
  • Complicate the management of conditions that Eliquis is prescribed for, such as atrial fibrillation or deep vein thrombosis.

Impact on Overall Cardiovascular Health

 

Maintaining good cardiovascular health is crucial when on Eliquis. Consuming too many processed and salty foods can lead to weight gain, increased cholesterol levels, and poor overall heart health, all of which can interfere with the effectiveness of your medication.

Weight Gain:

Processed foods are often high in calories and low in nutritional value, leading to weight gain. Excess weight can further strain the cardiovascular system.

Cholesterol Levels:

Many processed foods contain unhealthy fats that can raise cholesterol levels, contributing to the risk of heart disease.

Types of Processed Foods to Minimize

 

To maintain good health while on Eliquis, it’s important to minimize your intake of processed and salty foods.

Packaged Snacks:

Items like chips, pretzels, and crackers are typically high in sodium and unhealthy fats. Opt for fresh fruits and vegetables as healthier alternatives.

Processed Meats:

Sausages, hot dogs, and deli meats often contain high levels of sodium and preservatives. Choose lean cuts of fresh meat and poultry instead.

Convenience Foods:

Ready-to-eat meals, canned soups, and fast food are usually high in sodium and other additives.

Preparing meals from fresh ingredients can help you control sodium intake.

 

By reducing the consumption of processed and salty foods, you can help manage your blood pressure and improve overall heart health, ensuring that Eliquis can work effectively.

Always seek advice from your healthcare provider on the best dietary practices for your specific health needs.

 

Conclusion

While it’s important to be cautious of certain foods, remember that a balanced diet rich in fruits, vegetables, lean proteins, and whole grains is key to overall health.

Strive for moderation and variety in your food choices to support your well-being while managing your condition with Eliquis.

By staying informed and proactive about your diet and medication regimen, you can enhance the effectiveness of Eliquis and promote better health outcomes.

If you have any concerns or questions about your dietary choices while taking Eliquis, don’t hesitate to reach out to your healthcare provider for guidance and support.

Frequently Asked Questions (FAQs)

People also searched for questions related to foods to avoid while on Eliquis are:

Does Eliquis Have Food Restrictions?

Yes, Eliquis has some food restrictions. Certain foods can affect how well the medication works or increase the risk of side effects.

It’s important to be aware of these restrictions to ensure the medication is effective and safe.

Can You Eat Green Vegetables with Eliquis?

Green vegetables, especially leafy greens like spinach and kale, are high in Vitamin K, which can interfere with Eliquis.

You don’t need to avoid them completely, but it’s important to eat them in moderation and keep your intake consistent.

What Can You Not Mix with Eliquis?

Avoid mixing Eliquis with alcohol, grapefruit, and certain herbal supplements like St. John’s Wort and Ginkgo Biloba.

These can either increase the risk of bleeding or affect how well Eliquis works.

What Vitamins Should You Not Take with Eliquis?

Avoid taking large amounts of Vitamin K while on Eliquis. Vitamin K can counteract the blood-thinning effects of the medication.

Always consult your healthcare provider before starting any new vitamins or supplements.

Can I Take Turmeric with Eliquis?

Turmeric has blood-thinning properties, which can increase the risk of bleeding when taken with Eliquis.

It’s best to consult your healthcare provider before adding turmeric supplements to your diet.

Can You Eat Garlic with Eliquis?

Garlic also has blood-thinning effects. While small amounts used in cooking are generally safe, large amounts of garlic or garlic supplements should be avoided. Consult your healthcare provider for personalized advice.

Can I Eat Ginger with Eliquis?

Ginger, like garlic and turmeric, can thin the blood. Eating ginger in small amounts, such as in food or tea, is usually safe, but avoid large amounts and supplements without consulting your healthcare provider.

What Fruits Can You Eat with Eliquis?

Most fruits are safe to eat while taking Eliquis. However, you should avoid grapefruit and grapefruit juice as they can interfere with the medication. Berries, apples, bananas, and oranges (excluding grapefruit) are good options.

Which Vitamin Should Be Avoided if You Are Taking Blood Thinners?

Vitamin K should be avoided or consumed in consistent amounts if you are taking blood thinners like Eliquis.

It can counteract the effects of the medication. Foods high in Vitamin K include leafy green vegetables.

Can I Take Omega-3 While on Eliquis?

Omega-3 fatty acids have blood-thinning properties, so taking them with Eliquis can increase the risk of bleeding. It’s best to consult your healthcare provider before taking Omega-3 supplements.

Is It Safe to Take Vitamin C with Eliquis?

Yes, it is generally safe to take Vitamin C with Eliquis. There are no known interactions between Vitamin C and Eliquis. However, always check with your healthcare provider before adding any new supplements.

Can You Take Vitamin B12 with Eliquis?

Yes, you can take Vitamin B12 with Eliquis. There are no known interactions between Vitamin B12 and Eliquis, making it safe to include in your diet or supplement regimen.

Can You Drink Tea with Eliquis?

Most teas are safe to drink with Eliquis, but you should be cautious with green tea as it contains Vitamin K. Herbal teas, such as chamomile, should also be consumed in moderation due to potential blood-thinning effects.

Can I Take Calcium with Eliquis?

Yes, it is generally safe to take calcium with Eliquis. There are no known interactions between calcium supplements and Eliquis, but it’s always a good idea to consult your healthcare provider.

Can Vitamin D3 Be Taken with Eliquis?

Yes, Vitamin D3 can be taken with Eliquis. There are no known interactions between Vitamin D3 and Eliquis, making it safe to include in your supplement regimen.

Can I Take Eliquis Once a Day Instead of Twice?

Eliquis is typically prescribed to be taken twice a day to maintain consistent blood levels of the medication.

Do not change your dosage schedule without consulting your healthcare provider, as doing so could reduce the effectiveness of the medication.

What Are the Long-Term Effects of Taking Eliquis?

Long-term use of Eliquis can be associated with an increased risk of bleeding. Regular monitoring by your healthcare provider is necessary to manage any potential side effects.

The benefits of preventing blood clots often outweigh the risks of long-term use.

Is Eliquis Bad for Your Kidneys?

Eliquis is generally considered safe for the kidneys. Unlike some other blood thinners, it does not require extensive monitoring of kidney function.

However, people with severe kidney issues should use Eliquis cautiously and under close medical supervision.

What Organs Does Eliquis Affect?

Eliquis primarily affects the liver and the blood clotting system. It works by inhibiting specific clotting factors in the blood, which helps prevent clots from forming.

Do You Stay on Eliquis for Life?

Whether you stay on Eliquis for life depends on your individual medical condition. Some people may need to take it long-term to prevent blood clots, while others may use it temporarily.

Your healthcare provider will determine the duration based on your health needs.

 

Also Read:

 

Sertraline: 5 Foods to avoid when taking and Side Effects

Creon: 6 Foods to Avoid when taking & (Best Foods to eat)

 

Medically reviewed by Dr. Ramesh Gaddam, M.D.


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